Strain Profile: Do-Si-Dos Genetics, THC, Terpenes, Effects, Yield & More
- Breeders Collective
- Dec 2
- 13 min read
Do-Si-Dos: The Potent Cookies Descendant That Redefined Modern Indicas
Do-Si-Dos is one of the most powerful and influential strains to emerge from the Cookies genetic ecosystem. Known for its heavy-hitting potency, dense structure, and loud gas-cookie-funk aroma, Do-Si-Dos became a defining strain of the late 2010s and helped shape the next generation of dessert-gas hybrids. It brought a level of depth, strength, and complexity to the Cookies family that pushed the lineage into a new era of hybrid design.
While many dessert strains lean toward sweetness and cream, Do-Si-Dos delivered something darker and more resinous. It added OG-influenced gas, pungent floral notes, and a powerful sedative quality to the Cookies blueprint, which made it a favorite for connoisseurs, pheno hunters, and breeders looking for serious potency.
Origins and Genetic Background
Do-Si-Dos was developed by Archive Seed Bank, a breeding group known for its work with potent, OG-forward genetics. The strain was created by combining a classic Cookies phenotype with a powerhouse Kush cut:
Girl Scout Cookies (Forum Cut)
OGKB (OG Kush Breath)
This lineage gave Do-Si-Dos the perfect combination of dessert sweetness, earthy gas, and heavy indica strength.
Girl Scout Cookies (Forum Cut) Influence
The Forum Cut provides sweet, doughy, cookie-like terps, strong hybrid potency, and the iconic Cookies structure. It contributes the dessert side of the profile.
OGKB (OG Kush Breath) Influence
OGKB is a highly potent Kush descendant known for its earthy funk, deep gas, and heavy body effects. This parent is responsible for the pungency, the resin production, and Do-Si-Dos’s unmistakable knockout strength.
Together, these genetics formed a Cookies strain with far more gas and weight than earlier dessert hybrids.
Terpenes and Aroma Profile
Do-Si-Dos has a terpene profile that blends cookie sweetness with sharp, earthy depth. It stands out among Cookies descendants for its complexity and power.
Common terpenes include:
Caryophyllene
Limonene
Linalool
Myrcene
This terpene structure creates a sensory profile often described as:
Sweet cookie dough
Pungent earth
Gas and OG funk
Floral spice
Herbal coolness
What makes Do-Si-Dos unique is the combination of bright cookie sweetness on the front followed by a deep, gassy, earthy finish.
Cannabinoid Profile
Do-Si-Dos is known for exceptionally high THC levels, often ranging between 20 and 30 percent depending on the cut. CBD content is usually low. The overall potency is considered among the strongest within the Cookies lineage.
This high-THC, terpene-rich profile creates a heavy, immersive experience that made Do-Si-Dos a standout strain in premium markets. Its potency also made it a desirable parent for breeders looking to dial up strength in dessert-leaning hybrids.
Effects and Experience
Do-Si-Dos is typically described as an indica-leaning hybrid with a strong, long-lasting effect profile.
Mental Effects
The initial onset often brings a wave of euphoria, calm, and mental release. The high can feel introspective, dreamy, or tranquil.
Physical Effects
The physical experience is intense, delivering deep body relaxation, heaviness, and a pronounced couchlock quality at higher doses. Do-Si-Dos is widely regarded as one of the strongest body-heavy strains in the dessert-gas category.
Its balance of mental calm and full-body power made it a favorite for consumers seeking a louder, deeper version of traditional Cookies hybrids.
Phenotypes and Variations
Do-Si-Dos has produced several phenotypes and expressions, some emphasizing:
Sweeter cookie-forward terpenes
Heavier gas and earth
Purple coloration and high frost
Denser OG-influenced structure
Many growers consider Do-Si-Dos to be a breeder-friendly strain, producing stable, consistent traits that carry strongly into hybrids.
Descendants and Influence
Do-Si-Dos has had a major impact on modern genetics. It anchors a large family of potent dessert-gas hybrids and has been used in countless breeding projects that aim to enhance potency, resin production, and terpene density.
Notable descendants include:
Moonbow (Do-Si-Dos × Zkittlez)
Rainbow Belts (Moonbow × Zkittlez derivatives)
Peanut Butter Breath (Do-Si-Dos × Mendo Breath)
Dosi-Do variations and reversals used in boutique breeding
Its influence is especially strong in strains that blend candy-forward terps (Zkittlez, Sherbet, Gelato) with deeper, earthy gas foundations.
Cultural Significance
Do-Si-Dos holds a vital place in cannabis evolution. Its cultural and genetic impact includes:
Bringing high-potency OG funk into the Cookies family.
Helping define the modern dessert-gas hybrid category.
Serving as the parent of some of the most hyped strains in today’s market, including Moonbow and Rainbow Belts.
Showing that Cookies-descendants could be darker, heavier, and more powerful than their predecessors.
Becoming a foundational building block for new-wave designer exotics.
Do-Si-Dos bridged two of the most influential genetic lineages—Cookies and OG Kush—and created something that felt entirely new. Its potency and terpene depth continue to shape the direction of modern hybrid breeding. Browse some stand out Do Si Dos cannabis seed varieties availible at Breeders Collective cannabis seed bank:
Do Si Dos Auto by Auto Seeds is a compact, 70% indica autoflower created from Girl Scout Cookies × Face Off OG × Ruderalis, combining dessert-like sweetness with heavy potency and rapid growth. Delivering THC levels over 25%, this strain offers deep relaxation and tranquillity without excessive couchlock, carried by dense, resinous buds rich in earthy Kush notes, caramel, brown sugar, pine, and a hint of skunk. Its aroma mirrors these flavours, blending sweet, dessert-style richness with classic Kush depth. Growing 60–100 cm tall and finishing in 8–9 weeks from seed, Do Si Dos Auto produces impressive yields of 500–600 g/m², making it a fast, beginner-friendly yet high-end option for cultivators seeking strong effects, bold flavour, and reliable performance.
Dos Si Dos Auto by Barney’s Farm Seeds is a 65% indica autoflower crafted from Dos Si Dos × BF Super Auto #1, delivering a flavour-rich, potent, and fast-producing hybrid. With 23% THC, it offers a smooth mix of uplifting mental clarity and a relaxing, stone-like body buzz, wrapped in sweet earthy-cookie aromas layered with citrus, lime, and lemon-meringue notes. Its flavour leans toward fruity lemon and dessert-like sweetness, making it both refreshing and indulgent. Growing 80–110 cm indoors (up to 140 cm outdoors) and finishing in just 70–75 days, this strain rewards cultivators with heavy yields of 550–650 g/m² indoors and dense, resin-rich buds. Aromatic, flavourful, and efficient, Dos Si Dos Auto delivers high performance and balanced effects in a compact, easy-to-grow package.
Don Do Si Dos by Don’t Avalanche Seeds is a powerful 50/50 hybrid born from Girl Scout Cookies × Face Off OG, offering a high-THC, creativity-boosting experience wrapped in sweet, skunky flavour. With THC levels reaching up to 30%, this photoperiod strain delivers an intense, long-lasting cerebral high that enhances focus and sparks conversation before settling into a smooth, relaxing body effect. Its aroma blends fruity sweetness with earthy-skunk undertones, while the taste layers sugary fruit notes over a classic Kush-like musk. Flowering in 8–10 weeks and growing to a medium height with dense, trichome-heavy lime-green and lavender buds, Don Do Si Dos produces medium yields but excels in resin output and visual appeal. Ideal for seasoned users, it’s a flavourful, potent strain that balances psychoactive lift with soothing physical calm.
Do-Si-Dos Z by The Plug Seedbank is a balanced, resin-heavy hybrid created from Dosidos × Watermelon Z, offering dense, high-yielding buds packed with sweet tropical flavour and earthy depth. Flowering in 9–10 weeks, this feminised photoperiod strain grows to a manageable medium height with strong branching, making it ideal for both beginners and experienced cultivators—especially hash makers drawn to its exceptional trichome production. Its aroma blends fruity sweetness with subtle earthiness, while the flavour delivers tropical fruit, citrus zest, and creamy notes. Effects are uplifting and euphoric at first, followed by a smooth, relaxing body high that suits both daytime creativity and evening unwinding, making Do-Si-Dos Z a versatile, flavour-rich choice for quality-focused growers.
Dos Si Dos 33 by Barney’s Farm Seeds is a potent 60% indica hybrid crafted from Dos Si Dos × Gelato #33, delivering exceptional Cali-style production, rich dessert flavours, and a deeply euphoric yet relaxing high. With 22–28% THC, this feminised photoperiod strain produces dense lime-green and violet buds coated in heavy resin, carrying sweet, earthy cookie aromas accented by subtle Gelato creaminess. Indoors it grows compact at 90–110 cm, yielding an impressive 650–750 g/m², while outdoor plants can reach massive sizes, producing up to 2 kg per plant with a mid-October finish. Its effects begin with a bright, euphoric lift before melting into tranquil, sedative body relaxation, making Dos Si Dos 33 a premium option for growers and connoisseurs seeking potency, flavour, and standout harvests.
Alien Technology x Do-Si-Dos by Empire Seeds is a potent 80% indica hybrid created from Alien Technology × Do-Si-Dos, delivering 23–27% THC and a rich blend of kush, floral, and citrus flavours. Flowering in 7–9 weeks, this feminised photoperiod strain grows to a medium height with sturdy branching and dense, resin-heavy buds that reward growers with 350–450 g/m² indoors and up to 600 g per plant outdoors. Its aroma carries hashish, kush, and sweet floral tones, while the flavour balances citrus brightness with earthy kush depth. The high begins with an uplifting cerebral buzz before settling into a deeply relaxing full-body calm, making it ideal for evening unwinding, stress relief, and soothing physical tension.
Don Do Si Punch by Don Avalanche Seeds is a potent 60% indica hybrid created from Do-Si-Dos × Purple Punch, delivering a deeply relaxing, berry-sweet experience ideal for evening use. With THC levels reaching up to 29%, this photoperiod strain produces medium–high yields of large, resin-frosted buds displaying dark purples, forest greens, and vibrant orange pistils. Its aroma blends sweet berries, tropical fruit, and herbal spice, while the flavour follows with fruity, dessert-like richness and a subtle spicy finish. Flowering in 8–9 weeks, Don Do Si Punch grows to a manageable medium height with a bushy structure that benefits from pruning and airflow. The effects begin with a euphoric uplift before melting into full-body sedation, making this strain perfect for insomnia relief, chronic pain, and deep end-of-day relaxation.
Don Do Si Glue by Don Avalanche Seeds is a powerful 60% Sativa hybrid created from Do-Si-Dos × Gorilla Glue, delivering soaring THC levels of up to 32% and a bold blend of diesel, coffee, sweetness, and earthy-skunky undertones. Flowering in 8–9 weeks, this feminised photoperiod strain grows to a medium height and produces dense, resin-soaked buds that may need support late in bloom, rewarding cultivators with medium-to-high yields. Its aroma is rich with diesel and earthy sweetness, while the flavour layers sweet diesel and coffee over a skunky, earthy base. The high begins with an uplifting, creative cerebral buzz before easing into a smooth, relaxing body effect that avoids full couchlock unless heavily consumed, making Don Do Si Glue a potent, flavour-packed choice for experienced users seeking both mental stimulation and physical calm. Don Do Si Cookies Feminised By Don Avalanche
Don Do Si Cookies by Don Avalanche Seeds is a potent 55% Indica hybrid created from Do-Si-Dos × Girl Scout Cookies, uniting two GSC-driven lineages for a flavour-rich, euphoric, and deeply relaxing experience. With THC levels reaching up to 30%, this feminised photoperiod strain produces dense, resin-heavy buds in 8–9 weeks, showing light green flowers with purple highlights and bright orange pistils. Its aroma combines earthy sweetness with soft floral notes, while the flavour delivers smooth cookie-like sweetness layered over floral and earthy undertones. The high begins with an uplifting wave of creativity and happiness before easing into long-lasting physical calm, making Don Do Si Cookies ideal for both daytime inspiration and evening stress relief. Medium in height and offering medium-to-high yields, it’s a standout choice for growers seeking potency, flavour, and visually striking buds.
Do-Sweet-Dos by Sweet Seeds is a 65% indica feminised strain derived from elite Do-Si-Dos genetics, blending OGKB × Face-Off OG BX1 to create a sweet, earthy, and powerfully relaxing hybrid. With 17–24% THC, it delivers soothing, full-body effects ideal for stress relief, pain, anxiety, or evening unwinding. Its aroma mixes sugary earthiness with spicy, citrus, and floral undertones, while the flavour follows with sweet, earthy notes brightened by citrus and a hint of spice. Flowering in 9–10 weeks, Do-Sweet-Dos produces 450–550 g/m² indoors or 350–500 g per plant outdoors, forming compact, resin-rich buds with large calyxes perfect for extractions. Vigorous, robust, and suited to all grow levels, this strain offers a balanced Cookies-style profile with potent relaxation and rich terpene depth.
Do Si Dos Cookies by 00 Seeds is an indica-dominant feminised hybrid created from Girl Scout Cookies × Do Si Dos, producing compact, resinous plants indoors and towering specimens outdoors. With a fast 50–55 day flowering time, this photoperiod strain grows 80–100 cm indoors and up to 250 cm outdoors, yielding as much as 550 g/m² of heavy, dense buds. Its aroma is rich and dessert-like, blending pronounced chocolate and mint with sweet, earthy, and pine notes, creating an “After Eight”-style profile that sets it apart from typical Cookies hybrids. The effects are deeply relaxing and soothing for both mind and body, making it a perfect evening strain for unwinding. Combining quick turnaround, strong yields, and indulgent flavours, Do Si Dos Cookies is a rewarding option for growers seeking potency and sensory appeal.
Do-G by Ripper Seeds is a potent 50/50 hybrid created from White Fire OG (Wifi #43) × Do-Si-Dos, delivering a hard-hitting blend of OG gas and creamy cookie sweetness. Flowering in 60–65 days indoors and ready by mid-October outdoors, this feminised photoperiod strain grows medium to tall with notable stretch, producing high yields of dense, resin-soaked buds ideal for both smokers and extractors. Its aroma hits with earthy gas and sour sharpness, while the flavour mixes fuel, sour earth, and cookie-dough richness with a lingering retro sweetness. The effects strike heavily in the body before easing into an intoxicating, dreamy headspace, offering deep relaxation with a drifting mental haze. Easy to grow and highly productive, Do-G stands out as a flavour-packed powerhouse for fans of strong OG and Cookies genetics.
Do Si Dos #4 by Advanced Seeds is a potent regular hybrid prized for its dense, resin-rich buds, very high THC, and refined citrus–kush flavour profile. Flowering in 55–60 days, this photoperiod strain grows 90–120 cm indoors and up to 3 metres outdoors, yielding 400–450 g/m² of sticky, top-grade flowers ideal for both cultivation and breeding projects. Its aroma blends bright citrus with kush depth and light floral notes, mirrored in a bold yet smooth flavour. The effects are deeply relaxing, long-lasting, and body-heavy, making it a powerful choice for those seeking intensity and calm. With strong structure, easy cultivation, and classic Do Si Dos resin production, Do Si Dos #4 stands out as a premium genetic line for growers and breeders alike.
Do Si Dos Cookies Fast by 00 Seeds is a compact, indica-dominant hybrid created from Do-Si-Dos × Girl Scout Cookies, delivering fast flowering, strong potency, and classic Cookies-style flavours. With a shortened 55-day indoor flowering time and an outdoor finish by the last week of summer, this feminised photoperiod strain maintains excellent productivity, yielding up to 550 g/m² indoors while forming dense, resin-coated flowers along a sturdy central stem. Its aroma blends sweet, earthy, and piney notes, supported by terpenes like myrcene and pinene, while THC levels reaching up to 23% provide a relaxing, long-lasting body effect ideal for unwinding. Efficient, flavourful, and quick to finish, Do Si Dos Cookies Fast is a rewarding option for growers who want speed without sacrificing quality.
D’oh Si D’ohpe by Dr Krippling Seeds is a flavour-rich, mostly indica hybrid created from Girl Scout Cookie Do-Si-Dos × Super Skunk, delivering fast flowering, big yields, and a dessert-meets-skunk terpene punch. With 19–21% THC, this feminised photoperiod strain flowers in just 7–8 weeks, producing 500–600 g/m² indoors and up to 1100 g per plant outdoors of dense, resin-heavy buds. Its aroma blends sweet cookie dough and vanilla with earthy, skunky undertones, while the flavour adds spicy, musky notes for a rich, layered smoke. Effects are euphoric, relaxing, and body-soothing, offering a blissful mental lift paired with deep physical calm. Easy to grow and highly productive, D’oh Si D’ohpe combines speed, strength, and standout flavour for growers and consumers seeking a reliable, terpene-loaded indica.
Do-Si-Dos Auto by Original Sensible Seed Company is a compact, mostly indica autoflower created from Do-Si-Dos OG × Girl Scout Cookies Auto, delivering rich earthy-sweet flavours, fast finishing times, and deeply relaxing effects. Ready in just 65–75 days from seed, it grows 80–100 cm tall and produces impressive yields of up to 650 g/m² indoors or around 150 g per plant outdoors. With 20% THC, the high begins with a euphoric, uplifting buzz before settling into a soothing full-body calm ideal for evening unwinding. Its aroma blends sweet floral notes with earthy undertones, while the flavour carries classic earthy Kush enriched by floral and light citrus hints. Easy to grow, resilient, and packed with dense, trichome-covered buds, Do-Si-Dos Auto offers fast, flavourful, and reliable performance for growers of any level.
Do-Si-Dos Automatic by Royal Queen Seeds is a fast, flavour-packed 60% indica autoflower created from Do-Si-Dos × Cookies Auto, delivering around 20% THC, sweet earthy-citrus flavours, and a smooth, relaxing evening high. Completing its life cycle in just 9–10 weeks from germination, it grows 80–120 cm indoors and up to 140 cm outdoors, producing 350–400 g/m² inside with satisfying yields outside. Its aroma blends sweetness with earthy and citrus undertones, mirrored in a rich, balanced flavour profile. The effects are peaceful and soothing, ideal for unwinding without overwhelming sedation. Easy, efficient, and high-quality, Do-Si-Dos Automatic offers the potency and taste of its photoperiod parent in a quick, beginner-friendly autoflowering format.
Do-Si-Dos by Big Head Seeds (also listed by Black Skull Seeds) is a powerhouse, mostly indica hybrid crafted from Girl Scout Cookies × Face Off OG, delivering 25–30% THC, dense resin-soaked buds, and a bold lime–mint aroma with earthy pine depth. Flowering in 9 weeks indoors and finishing outdoors by early October, this feminised photoperiod strain grows to a medium height with compact, heavy colas and yields high volumes of visually striking lavender, orange, and green buds coated in trichomes. Its flavour blends earthy pine with citrus and herbal mint accents, while the effects begin with a euphoric, happy lift that transitions into a long-lasting, deeply calming body high. Potent, flavourful, and highly productive, Do-Si-Dos is a standout choice for growers and users seeking maximum strength and sensory appeal.
Do-Si-Dos OG by Original Sensible Seed Company is a powerhouse 70% indica hybrid created from Do-Si-Dos × Colorado Ghost OG, delivering up to 28% THC, heavy yields, and a rich cookies-and-cream flavour wrapped in fruity, diesel-earth undertones. Flowering in 60–65 days, this feminised strain produces dense, resin-loaded buds with lime-green and lavender tones, yielding up to 600 g/m² indoors and 800 g per plant outdoors. Its aroma is pungent, sweet, and fruity with hints of wood and herbs, while the smoke blends creamy cookie notes with earthy and fruity depth. The effects hit fast with a potent full-body stone lifted by an energising, euphoric mental buzz—perfect for evening relaxation, stress relief, and appetite stimulation. Potent, aromatic, and highly productive, Do-Si-Dos OG is a gourmet-grade strain for growers and connoisseurs seeking West Coast power and flavour.
Auto Do-Si-Dos Cookies by 00 Seeds is a potent, indica-dominant autoflower that preserves the Californian character of its parent strain while delivering fast, abundant, and flavour-packed harvests. Reaching 22% THC, it produces dense, resinous buds in 80–90 days indoors (April–November outdoors), yielding 450–500 g/m² and growing to a manageable 80–90 cm indoors or 110–130 cm outdoors. Its aroma is rich and dessert-like, mixing sweetness with chocolate, mint, earth, and pine, while the flavour carries chocolate-mint notes layered over earthy undertones. The effects offer strong mental and physical relaxation paired with a gentle sense of happiness, making Auto Do-Si-Dos Cookies a perfect evening strain for unwinding with a smooth, indulgent terpene profile and reliable, easy cultivation. For a full list of do Si Dos cannabis seeds available at Breeders Collective see here.
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